Self-assembling amphiphilic poly(propargyl methacrylate) grafted DNA copolymers into multi-strand helices.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26096216.
- Also identified by DOI 10.1039/c5sm01325a.
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Abstract
DNA was covalently grafted onto poly(propargyl methacrylate) (PPMA) via "click" chemistry to synthesize the amphiphilic polymer brush. The PPMA-g-DNA brush could assemble into a primary structure of a nanofiber, which can be compactly spun into a multiple-strand helix in micron-length. The brush could also self-assemble with DNA labelled gold nanoparticles.
Medical subject headings
- DNA
- Methacrylates
- Nanoparticles
- Polymers