Targeted Therapy for Breast Cancer Stem Cells by Liposomal Delivery of siRNA against Fibronectin EDB.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26097122.
- Also identified by DOI 10.1002/adhm.201500190.
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Abstract
Targeted therapy for breast cancer stem cell (BCSC): A novel liposomal system (APTEDB -LS-siRNA(EDB) ) that enables simultaneous targeting and knockdown of extra domain B of fibronectin (EDB-FN) shows potent therapeutic efficacy in the BCSC-derived tumors in vivo.
Medical subject headings
- Fibronectins
- Liposomes
- Neoplastic Stem Cells
- RNA, Small Interfering