Solitaire FR revascularization device 4×40: safety study and effectiveness in preclinical models.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26101268.
- Also identified by DOI 10.1136/neurintsurg-2015-011856.
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Abstract
Recent randomized clinical trials have shown the benefit of stent retrievers for endovascular intervention in patients with acute ischemic stroke. The Solitaire 2 FR 4×40 device was developed to address longer clots as well as procedural difficulties. This study was undertaken to evaluate the safety of the new device in a swine model at 0, 30, and 90 days as well as its in vitro effectiveness. There were no significant differences in the overall animal health, tissue injury, hemorrhagic or thrombogenic events related to device usage. Based on the comparison at multiple time points, the Solitaire 2 4×40 device was similar in safety and usability to the Solitaire 2 4×20 device. Due to the additional length of the device, the Solitaire 2 4×40 device may in fact provide a number of additional technical benefits in the neurothrombectomy treatment of ischemic stroke.
Medical subject headings
- Brain Ischemia
- Cerebral Revascularization
- Disease Models, Animal
- Stroke
- Thrombectomy