Selenite-Releasing Bone Mineral Nanoparticles Retard Bone Tumor Growth and Improve Healthy Tissue Functions In Vivo.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26101804.
- Also identified by DOI 10.1002/adhm.201500307 and PMC identifier 4551614.
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Abstract
Selenite-doped bone mineral nanoparticles can retard the growth of osteosarcoma in a nude mice model, through sustained release of selenite ions. The selenite ions released from the nanoparticles through a degradation-mediated fashion inhibit tumor metastasis. Blood routine analysis indicates that selenite ions can also improve the functions of liver, kidney, and heart.
Medical subject headings
- Bone Density
- Bone Neoplasms
- Nanoparticles
- Selenious Acid