Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26108605.
- Also identified by DOI 10.1038/ncomms8344 and PMC identifier 4491171.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina. Analyses of this genome and the 14,544 predicted protein-encoding genes provide unique insights into the fly's molecular biology, interactions with the host animal and insecticide resistance. These insights have broad implications for designing new methods for the prevention and control of myiasis.
Medical subject headings
- Diptera
- Gene Expression Regulation
- Genome, Insect
- Insect Proteins