Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders.

Yoon, Jaewon; Eyster, Tom W; Misra, Asish C; Lahann, Joerg · Adv Mater · 2015

basic_science · Level V

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Abstract

Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardio-myocyte contraction. These microcylinders can find applications in a host of micromechanical systems.