Differentiated Thyroid Cancer in Children: Prevalence and Predictors in a Large Cohort with Thyroid Nodules Followed Prospectively.

Papendieck, Patricia; Gruñeiro-Papendieck, Laura; Venara, Marcela; Acha, Oscar; Cozzani, Hugo; Mateos, Fernanda; Maglio, Silvana; Calcagno, Maria Lujan et al. · J Pediatr · 2015

retrospective_cohort · Level III

Where this comes from

Abstract

We retrospectively analyzed the findings of a prospective cohort of 75 children referred for thyroid nodules between 2008 and 2013. Prevalence of papillary differentiated thyroid carcinoma was 18.7%. Thyrotropin >2.5 mIU/L, multinodular goiter, solid nodules, irregular margins, and pathologic lymphadenopathies were identified as independent predictors of malignancy.

Medical subject headings