Invited commentary on … Lithium treatment and risk for dementia in adults with bipolar disorder.

Sutherland, Calum; Duthie, Ashleigh C · Br J Psychiatry · 2015

editorial · Level V

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Abstract

Alzheimer's disease clinical trials are failing at an alarming rate, highlighting the desperate need for novel thinking to combat this escalating health crisis. A recent large-scale population study indicates that lithium treatment reduces dementia development, supporting preclinical mechanistic evidence that this commonly used agent might be clinically valuable in dementia.

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