From Prescription to Transcription: Genome Sequence as Drug Target.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26140587.
- Also identified by DOI 10.1016/j.cell.2015.06.033.
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Abstract
Personalizing treatments to account for genetically mediated differences in drug responses is an exciting opportunity to improve patient outcomes. In this issue, Soccio et al. reveal new mechanisms by which non-coding variants alter the activity of the anti-diabetic drug rosiglitazone.
Medical subject headings
- Hypoglycemic Agents
- PPAR gamma
- Polymorphism, Single Nucleotide