AIMing 2 Curtail Cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26140588.
- Also identified by DOI 10.1016/j.cell.2015.06.041.
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Abstract
The dysregulation of the relationship between gut microbiota and innate immune homeostasis can lead to a range of complex diseases. In this issue, Man et al. reveal that the intracellular innate sensor AIM2 regulates microbial and stem cell homeostasis in the gut to protect against colorectal cancer.
Medical subject headings
- Cell Proliferation
- Colorectal Neoplasms
- DNA-Binding Proteins
- Stem Cells