From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26140603.
- Also identified by DOI 10.1016/j.stem.2015.06.013.
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Abstract
While iPSCs have created unprecedented opportunities for drug discovery, there remains uncertainty concerning the path to the clinic for candidate therapeutics discovered with their use. Here we share lessons that we learned, and believe are generalizable to similar efforts, while taking a discovery made using iPSCs into a clinical trial.
Medical subject headings
- Induced Pluripotent Stem Cells
- Models, Neurological