Complications After TKA in Patients With Hemophilia or Von Willebrand's Disease.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 26143236.
- Also identified by DOI 10.1016/j.arth.2015.06.015.
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Abstract
Little is known about perioperative complications following total knee arthroplasty (TKA) in patients with bleeding disorders. This study utilized a national database to evaluate postoperative complication rates and up to 8-year revision rates after TKA in patients with hemophilia (n=3396) and von Willebrand's disease (n=1379) compared to a matched cohort of patients without a bleeding disorder (n=427,132 and n=394,657 respectively). Hemophilia and von Willebrand's disease were associated with significantly higher rates of infection, transfusion of blood products, medical complications, and revision after TKA compared to matched controls. Hemophilia was associated with significantly higher rates of venous thromboembolism and transfusion compared to patients with von Willebrand's disease and matched controls after TKA.
Medical subject headings
- Arthroplasty, Replacement, Knee
- Hemophilia A
- Postoperative Complications
- von Willebrand Diseases
Anatomy
- knee