Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa.

Lim, Jennifer R; Gandhi, Neel R; Mthiyane, Thuli; Mlisana, Koleka; Moodley, Julie; Jaglal, Prenika; Ramdin, Neeshan; Brust, James C M et al. · PLoS One · 2015

prospective_cohort · Level II

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Abstract

South Africa is experiencing a widespread drug-resistant tuberculosis epidemic, although data are limited regarding the current situation. This study finds that the extensively drug-resistant tuberculosis (XDR-TB) incidence in KwaZulu-Natal increased to 3.5 cases/100,000 (776 cases) in 2011-2012. XDR-TB cases are widely distributed geographically, with the majority of districts experiencing a rise in incidence.

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