Biotunable acoustic node assembly of organoids.

Chen, Pu; Güven, Sinan; Usta, Osman Berk; Yarmush, Martin L; Demirci, Utkan · Adv Healthc Mater · 2015

basic_science · Level V

Where this comes from

Abstract

Bioengineering of 3D microtissues from cell spheroids is demonstrated by employing the vibration of acoustic standing waves and its hydrodynamic effect at the bottom of a liquid-carrier chamber. A large number of cell spheroids (>10(4) ) are assembled in seconds into a closely packed structure in a scaffold-free fashion under nodal pattern of the standing waves in a fluidic environment.

Medical subject headings