SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26151908.
- Also identified by DOI 10.1371/journal.pone.0132541 and PMC identifier 4495030.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg mL(-1)).
Medical subject headings
- Gallic Acid
- Organometallic Compounds
- Silicon Dioxide