Next Generation of Preclinical Liver Cancer Models.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26169964.
- Also identified by DOI 10.1158/1078-0432.CCR-15-1152.
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Abstract
Because of its heterogeneity, lack of prognostic markers, tumor-escape mechanisms, and frequent relapse upon surgical intervention, treatment of hepatocellular carcinoma (HCC) remains challenging. In this issue of Clinical Cancer Research, Groß and colleagues characterize a rodent model that might help identify novel drugs for combinatorial sorafenib-based therapies for HCC.
Medical subject headings
- Carcinoma, Hepatocellular
- Liver Neoplasms