Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index.
rct · Level II
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- Record sourced from PubMed, PMID 26178282.
- Also identified by DOI 10.3899/jrheum.140956.
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Abstract
To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis. Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection. The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97). This study supports the use of the CCI as a single-joint assessment after single-joint intervention. NTR-1210.
Medical subject headings
- Antirheumatic Agents
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Etanercept
- Knee Joint