Cancer: A dendritic-cell brake on antitumour immunity.
basic_science · Level V
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- Record sourced from PubMed, PMID 26178959.
- Also identified by DOI 10.1038/523294a and PMC identifier PMC2848068.
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Abstract
Activation of a cellular stress response and the transcription factor XBP1 in dendritic cells has now been shown to limit the cells' ability to stimulate antitumour immune responses in a mouse model of ovarian cancer.