A Luminogen with Aggregation-Induced Emission Characteristics for Wash-Free Bacterial Imaging, High-Throughput Antibiotics Screening and Bacterial Susceptibility Evaluation.

Zhao, Engui; Chen, Yilong; Chen, Sijie; Deng, Haiqin; Gui, Chen; Leung, Chris W T; Hong, Yuning; Lam, Jacky W Y et al. · Adv Mater · 2015

basic_science · Level V

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Abstract

A luminogen with aggregation-induced emission characteristics is reported for bacterial imaging and antibiotics screening studies. The luminogen can light up bacteria in a wash-free manner, which simplifies the imaging process and increases its accuracy in bacterial detection. It can also be applied to high-throughput screening of antibiotics and fast evaluation of bacterial susceptibility, giving reliable results in less than 5 h.

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