Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative.
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- Record sourced from PubMed, PMID 26185209.
- Also identified by DOI 10.1161/CIRCRESAHA.117.306693 and PMC identifier 4535701.
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Abstract
Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.
Medical subject headings
- Government Programs
- Heart Diseases
- Mitochondria, Heart
- Myocytes, Cardiac
- National Heart, Lung, and Blood Institute (U.S.)