Remodeling Your Way out of Cell Cycle.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26186182.
- Also identified by DOI 10.1016/j.cell.2015.06.050.
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Abstract
Throughout development, proliferative progenitors lose their mitotic potential, exit the cell cycle, and differentiate. In this issue, Ruijtenberg and van den Heuvel identify an important lineage-specific role for a SWI/SNF chromatin-remodeling complex that collaborates with core cell-cycle regulators to promote cell-cycle exit and terminal muscle cell differentiation.
Medical subject headings
- Caenorhabditis elegans
- Muscles