Taking the brakes off telomerase.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 26194808.
- Also identified by DOI 10.7554/eLife.09519 and PMC identifier 4507575.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Studies using human embryonic stem cells have revealed how common cancer-associated mutations exert their effect on telomerase after cells differentiate into more specialized cell types.
Medical subject headings
- Cell Proliferation
- Mutation
- Promoter Regions, Genetic
- Telomerase