(18)F-FDG PET/CT and Melanoma: Staging, Immune Modulation and Mutation-Targeted Therapy Assessment, and Prognosis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26204273.
- Also identified by DOI 10.2214/AJR.14.13575.
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Abstract
Monoclonal antibodies that target the programmed cell death 1 (PD-1) immune checkpoint protein and its associated ligands, PD-L1 and PD-L2, and targeted inhibitors of mutated signal transduction molecules such as BRAF inhibitors show immense promise in treating patients with melanoma. We discuss the use of (18)F-FDG PET/CT for assessing therapy effectiveness, staging advanced disease, and determining prognosis of patients with melanoma. FDG PET/CT is useful in staging disease, assessing therapy, and determining prognosis in patients with melanoma.
Medical subject headings
- Antineoplastic Agents
- Immunotherapy
- Melanoma
- Multimodal Imaging
- Positron-Emission Tomography
- Tomography, X-Ray Computed