Cortical folding and the potential for prognostic neuroimaging in schizophrenia.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 26206860.
- Also identified by DOI 10.1192/bjp.bp.114.155796 and PMC identifier 4629075.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
In 41 patients with schizophrenia, we used neuroanatomical information derived from structural imaging to identify patients with more severe illness, characterised by high symptom burden, low processing speed, high degree of illness persistence and lower social and occupational functional capacity. Cortical folding, but not thickness or volume, showed a high discriminatory ability in correctly identifying patients with more severe illness.
Medical subject headings
- Cerebral Cortex
- Magnetic Resonance Imaging
- Neuroimaging
- Schizophrenia