Engineering Melanin Nanoparticles as an Efficient Drug-Delivery System for Imaging-Guided Chemotherapy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26222210.
- Also identified by DOI 10.1002/adma.201502201.
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Abstract
In order to promote imaging-guided chemotherapy for preclinical and clinical applications, endogenous nanosystems with both contrast and drug-delivery properties are highly desired. Here, the simple use of melanin is first reported, and this biopolymer with good biocompatibility and biodegradability, binding ability to drugs and ions, and intrinsic photoacoustic properties, can serve as an efficient endogenous nanosystem for imaging-guided tumor chemotherapy in living mice.
Medical subject headings
- Antineoplastic Agents
- Drug Carriers
- Engineering
- Melanins
- Nanoparticles
- Photoacoustic Techniques