Imaging Tumor Acidity: pH-Low Insertion Peptide Probe for Optoacoustic Tomography.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26224874.
- Also identified by DOI 10.1158/1078-0432.CCR-15-1502 and PMC identifier 4609264.
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Abstract
Optoacoustic tomography has been used for the detection of pancreatic ductal adenocarcinoma targeted by pH-low insertion peptide (pHLIP) conjugated to near-infrared fluorescent dye. It was proved that tumor targeting is pH dependent. The approach could have major implication for detection and monitoring of pancreatic and other cancers.
Medical subject headings
- Adenocarcinoma
- Membrane Proteins
- Pancreatic Neoplasms