Daughter's Tolerance of Mom Matters in Mate Choice.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26232215.
- Also identified by DOI 10.1016/j.cell.2015.07.030 and PMC identifier 4669059.
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Abstract
Mendelian genetics presumes inheritance of fitness through DNA. Kinder et al. find that maternal microchimerism induces stable immune tolerance to non-inherited maternal antigens in offspring. Female offspring that share these antigens with their mate experience reduced fetal wasting, establishing a role for vertical transmission of non-genetic information in reproductive fitness.
Medical subject headings
- Fetus
- Genetic Fitness
- Immune Tolerance
- Mammals
- Pregnancy
- T-Lymphocytes, Regulatory