Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control.

Diamond, Michael S; Pierson, Theodore C · Cell · 2015

review · Level V

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Abstract

Dengue virus (DENV) is a mosquito-transmitted RNA virus that infects an estimated 390 million humans each year. Here, we review recent advances in our understanding of the biology of DENV and describe knowledge gaps that have impacted the development of effective vaccines and therapeutics.

Medical subject headings