Dissolvable base scaffolds allow tissue penetration of high-aspect-ratio flexible microneedles.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26239876.
- Also identified by DOI 10.1002/adhm.201500305.
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Abstract
Microscale needle technology is important in electrophysiological studies, drug/chemical delivery systems, optogenetic applications, and so on. In this study, dissolvable needle-base scaffold realizes penetration of high-aspect-ratio flexible microneedles (e.g., <5 μm diameter and >500 μm length) into biological tissues. This methodology, which is applicable to numerous high-aspect-ratio flexible microneedles, should reduce the invasiveness and provide safer tissue penetrations than conventional approaches.
Medical subject headings
- Needles