Type 1 Diabetes and MicroRNA: It's Complicated.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 26244930.
- Also identified by DOI 10.1016/j.cmet.2015.07.018.
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Abstract
Type 1 diabetes is an autoimmune disease that manifests as impaired insulin secretion, with compounding complications over time. Bhatt et al. (2015) investigate protective mechanisms in survivors of type 1 diabetes by using induced pluripotent stem cells as genetic models, uncovering novel interactions between microRNA and the DNA damage checkpoint pathway.
Medical subject headings
- Cell Cycle Checkpoints
- DNA Damage
- Diabetes Mellitus, Type 1
- Gene Expression Regulation
- MicroRNAs
- Models, Biological