Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging.

Pu, Kanyi; Mei, Jianguo; Jokerst, Jesse V; Hong, Guosong; Antaris, Alexander L; Chattopadhyay, Niladri; Shuhendler, Adam J; Kurosawa, Tadanori et al. · Adv Mater · 2015

basic_science · Level V

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Abstract

Diketopyrrolopyrrole-based semiconducting polymer nanoparticles with high photostability and strong photoacoustic brightness are designed and synthesized, which results in 5.3-fold photoacoustic signal enhancement in tumor xenografts after systemic administration.

Medical subject headings