Cell Cycle Rules Pluripotency.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26253197.
- Also identified by DOI 10.1016/j.stem.2015.07.019.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Stem cell self-renewal is intrinsically associated with cell cycle control. However, the precise mechanisms coordinating cell fate choices and cell cycle remain to be fully uncovered. Now in Cell, Gonzales et al. (2015) and colleagues demonstrate that factors controlling the G2/M phase are necessary to block pluripotency upon induction of differentiation.
Medical subject headings
- Cell Cycle
- Embryonic Stem Cells
- Gene Regulatory Networks