Droplet-Array (DA) Sandwich Chip: A Versatile Platform for High-Throughput Cell Screening Based on Superhydrophobic-Superhydrophilic Micropatterning.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26255809.
- Also identified by DOI 10.1002/adma.201502115.
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Abstract
A droplet-array (DA) sandwich chip is a miniaturized platform for cell-based high-throughput screening. It is based on sandwiching of a glass slide with a preprinted library and a superhydrophobic-superhydrophilic pattern, which consists of thousands of simultaneously formed microdroplets containing cells. The DA sandwich chip allows for one-step cell seeding, simultaneous initiation of screening, and 1000 times less reagent consumption than a regular 96-well plate.
Medical subject headings
- Hydrophobic and Hydrophilic Interactions
- Microfluidic Analytical Techniques
- Tissue Array Analysis