Rapid 3D Extrusion of Synthetic Tumor Microenvironments.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26283579.
- Also identified by DOI 10.1002/adma.201501729 and PMC identifier 4745120.
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Abstract
The spatial positioning of 3D tumor-mimetic microenvironments, containing multiple cell types, is controlled with a simple concentric flow device in a single step. A range of geometric architectures are demonstrated, and the migration of segregated tumor cells and macrophages is explored using drugs that inhibit heterotypic interactions.
Medical subject headings
- Microfluidics
- Tissue Scaffolds
- Tumor Microenvironment