Isotonic vs Hypotonic Intravenous Fluids for Hospitalized Children.

JAMA · 2015

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Abstract

CLINICAL QUESTION: Is isotonic fluid associated with a lower incidence of hyponatremia when compared with hypotonic fluid for maintenance intravenous fluid therapy in children? BOTTOM LINE: Compared with hypotonic fluid, isotonic fluid is associated with a lower incidence of hyponatremia, without evidence of an increase in adverse outcomes.