Daily movement patterns and predicted 10-yr risk for a first atherosclerotic cardiovascular disease (ASCVD) event using the pooled cohort risk equations among US adults.

Abstract

OBJECTIVE: Examine the association between movement patterns and predicted risk of a first atherosclerotic cardiovascular disease (ASCVD) event. METHODS: Data from the 2003-2006 National Health and Nutrition Examination Survey (NHANES) were used (40-79 yrs; N=2421). Participants wore an ActiGraph 7164 accelerometer to create four movement pattern groups; Group 1: ≥150 min/wk of moderate-to-vigorous physical activity (MVPA) and light-intensity physical activity (LIPA) ≥ sedentary behavior (SB); Group 2: ≥150 min/wk of MVPA and LIPA<SB; Group 3: <150 min/wk of MVPA and LIPA≥SED; and Group 4: <150 min/wk of MVPA and LIPA<SB. 10-yr risk for a first ASCVD event was estimated using the pooled cohort equations. RESULTS: After adjusting for age, gender, race-ethnicity and obesity, Group 2 (β=-0.28; p=0.44) was not significantly different than Group 1, but Groups 3 (β=1.09; p=0.01) and 4 (β=1.44; p<0.001) had a higher pooled risk score. CONCLUSIONS: Those in the least desirable movement pattern (Group 4) had the highest pooled risk score. Given the similar risk scores for Groups 1 and 2, future research is needed to determine if sufficient MVPA can counteract the potential consequences associated with an imbalanced LIPA:SB ratio (i.e., LIPA<SB).