An optical nanoruler based on a conjugated polymer-silver nanoprism pair for label-free protein detection.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26314928.
- Also identified by DOI 10.1002/adma.201502880.
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Abstract
An optical nanoruler system based on a conjugated polyelectrolyte-silver nanoprism pair is developed for label-free protein detection by taking advantage of the metal-enhanced fluorescence effect of silver nanostructures. Antibody-antigen interactions induce a change in the metal-fluorophore distance, followed by the response of a fluorescent signal of the conjugated polyelectrolyte. The system is used to detect target antigens sensitively and selectively.
Medical subject headings
- Antigens
- Nanotechnology
- Optical Devices
- Proteins