Grafted biomembranes containing membrane proteins--the case of the leucine transporter.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26325086.
- Also identified by DOI 10.1039/c5sm01490e.
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Abstract
Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.
Medical subject headings
- Amino Acid Transport Systems
- Molecular Dynamics Simulation