Core-Shell MnSe@Bi2 Se3 Fabricated via a Cation Exchange Method as Novel Nanotheranostics for Multimodal Imaging and Synergistic Thermoradiotherapy.

Song, Guosheng; Liang, Chao; Gong, Hua; Li, Meifang; Zheng, Xianchuang; Cheng, Liang; Yang, Kai; Jiang, Xiqun et al. · Adv Mater · 2015

basic_science · Level V

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Abstract

MnSe@Bi2 Se3 core-shell nanostructures with highly integrated imaging and therapy functions are fabricated by a simple cation exchange method. Using those nanoparticles as a theranostic agent, a promise concept is further demonstrated to enhance conventional radiotherapy by: i) using X-ray absorbing agents to locally concentrate radiation energy and ii) employing near-infrared-light-triggered photothermal therapy to overcome hypoxia-associated radioresistance.

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