Members Only: Hypoxia-Induced Cell-Cycle Activation in Cardiomyocytes.

Sharma, Arun; Wu, Sean M · Cell Metab · 2015

basic_science · Level V

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Abstract

A low level of cardiomyocyte turnover occurs in the adult mammalian heart, but the source of these new cells remains unknown. Kimura et al., 2015 utilized a novel hypoxia-induced fate mapping system to identify a rare population of adult cardiomyocytes undergoing cell-cycle entry and expansion in healthy adult hearts and following ischemic injury.

Medical subject headings