Releasing the Brakes on Cancer Immunotherapy.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26359975.
- Also identified by DOI 10.1016/j.cell.2015.08.038.
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Abstract
This year's Lasker∼DeBakey Clinical Research Award goes to James Allison for discovering that antibody blockade of the T cell molecule CTLA-4 unleashes the body's immune response against malignant tumors. This has led to development of multiple "immune checkpoint therapies" that are prolonging and saving the lives of thousands of cancer patients.
Medical subject headings
- Immunotherapy
- Neoplasms