Melatonin Lulling Th17 Cells to Sleep.

Lee, Jacob S; Cua, Daniel J · Cell · 2015

editorial · Level V

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Abstract

In this issue, Farez et al. report that the circadian hormone melatonin, whose levels vary with seasonal changes in night length, shifts the immune response toward an anti-inflammatory state that may explain the seasonal variability of multiple sclerosis disease activity.

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