Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 26366721.
- Also identified by DOI 10.1371/journal.pone.0137770 and PMC identifier 4569555.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples.
Medical subject headings
- MicroRNAs
- Polymorphism, Single Nucleotide
- Spondylitis, Ankylosing