Microfluidics using a thiol-acrylate resin for fluorescence-based pathogen detection assays.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26371689.
- Also identified by DOI 10.1039/c5lc00971e.
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Abstract
We demonstrate thiol-acrylate microfluidics prepared via soft lithography for single-step protein immobilization and fluorescence-based pathogen detection. Such microfluidics are formed via room temperature curing, and bonded without oxygen plasma. The background fluorescence of the resin was found to be similar to PDMS for several filter sets. We also show that thiol-acrylate devices are able to bond to gold-coated surfaces, which allows for integration with microfabricated sensors.
Medical subject headings
- Acrylic Resins
- Escherichia coli O157
- Microfluidic Analytical Techniques
- Sulfhydryl Compounds