CCR 20th Anniversary Commentary: Simpson's Paradox and Neoadjuvant Trials.

Carey, Lisa A · Clin Cancer Res · 2015

editorial · Level V

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Abstract

The research article by Carey and colleagues, published in the April 15, 2007, issue of Clinical Cancer Research, described the relationship between response to neoadjuvant chemotherapy and outcome by tumor subtype. Today neoadjuvant clinical trials are often designed to provide correlative data to help identify predictive biomarkers or to focus on poor-risk patients identified by residual disease after neoadjuvant treatment.

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