Releasing the Brake on Oncolytic Viral Therapy.
editorial · Level V
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- Record sourced from PubMed, PMID 26378034.
- Also identified by DOI 10.1158/1078-0432.CCR-15-1769.
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Abstract
Oncolytic virus that selectively targets and eradicates tumor cells and immune checkpoint blockade that unleashes host antitumor immune responses show synergistic effects against cancer. This combination holds great promise for future treatment of a broad range of cancers in patients. Clin Cancer Res; 21(24); 5417-9. ©2015 AACR.See related article by Rojas et al., p. 5543.
Medical subject headings
- Oncolytic Virotherapy
- Virus Replication