Improving folate (vitamin B9) stability in biofortified rice through metabolic engineering.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26389575.
- Also identified by DOI 10.1038/nbt.3358.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We show that folates in stored rice grains are unstable, which reduces the potential benefits of folate biofortification. We obtain folate concentrations that are up to 150 fold higher than those of wild-type rice by complexing folate to folate-binding proteins to improve folate stability, thereby enabling long-term storage of biofortified high-folate rice grains.
Medical subject headings
- Folic Acid
- Genetic Enhancement
- Metabolic Engineering
- Oryza