Multitheragnostic Multi-GNRs Crystal-Seeded Magnetic Nanoseaurchin for Enhanced In Vivo Mesenchymal-Stem-Cell Homing, Multimodal Imaging, and Stroke Therapy.
basic_science · Level V
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- Record sourced from PubMed, PMID 26403165.
- Also identified by DOI 10.1002/adma.201502784.
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Abstract
A multifunctional nanoseaurchin probe in which mesoporous silica nanobeads with iron oxide nanoparticles embedded and multi-gold nanorods crystal-seeded are fabricated and labeled with umbilical cord mesenchymal stem cells through endocytosis. This nanoplatform enables efficient magnetic remote-controlled guiding for stem cell homing, and provides dual modalities of photoacoustic imaging and magnetic resonance imaging for in situ tracking and long-term monitoring to achieve therapeutic efficacy.
Medical subject headings
- Gold
- Magnetite Nanoparticles
- Mesenchymal Stem Cell Transplantation
- Nanotubes
- Stroke