A sympathetic view on fat by leptin.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26406366.
- Also identified by DOI 10.1016/j.cell.2015.09.016.
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Abstract
Zeng et al. reveal that the lipolytic effect of the hormone leptin is mediated by sympathetic nerve fibers that directly "envelope" white adipocytes. Local activation of the sympathetic input to the fat opens new venues to circumvent central leptin resistance in obesity.
Medical subject headings
- Adipose Tissue, White
- Leptin
- Lipolysis