Revealing the complexity of retroviral repression.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26406368.
- Also identified by DOI 10.1016/j.cell.2015.09.014 and PMC identifier 6309249.
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Abstract
Retroviral restriction is a complex phenomenon that, despite remarkable recent progress, is far from being well understood. In this Preview, we introduce an insightful study by Yang et al. that represents the first attempt to identify the global determinants of retroviral repression in pluripotent mammalian cells.
Medical subject headings
- Embryonic Stem Cells
- Endogenous Retroviruses
- Proviruses